the kept record
Thymulin References and Citations
Every quantitative claim in this digest traces to one of these sources. The list runs from the metallochemistry that named thymulin to the modern gene-therapy work.
About this thymulin reference list
This thymulin reference list is the documentary backbone of the digest. Each entry carries journal, year, and — where one exists — a DOI and a PubMed (PMID) link, so any claim on the site can be checked against its source. The literature is small and weighted toward the late 1970s through the 2000s, with a modern gene-therapy thread; that shape is itself part of the honest picture. Entries marked without a DOI are older papers indexed in PubMed by PMID only. For the synthesis built on these sources, see the thymulin research findings.
- Dardenne M, Pléau JM, Nabarra B, Lefrancier P, Derrien M, Choay J, Bach JF. Contribution of zinc and other metals to the biological activity of the serum thymic factor. Proc Natl Acad Sci U S A. 1982;79(17):5370-3. ↗
- Dardenne M, Pléau JM. Interactions between zinc and thymulin. Met Based Drugs. 1994;1(2-3):233-9. ↗
- Prasad AS, Meftah S, Abdallah J, Kaplan J, Brewer GJ, Bach JF, Dardenne M. Serum thymulin in human zinc deficiency. J Clin Invest. 1988;82(4):1202-10. ↗
- Reggiani PC, Morel GR, Cónsole GM, Barbeito CG, Rodriguez SS, Brown OA, Bellini MJ, Pléau JM, Dardenne M, Goya RG. The thymus-neuroendocrine axis: physiology, molecular biology, and therapeutic potential of the thymic peptide thymulin. Ann N Y Acad Sci. 2009;1153:98-106. ↗
- Reggiani PC, Schwerdt JI, Cónsole GM, Roggero EA, Dardenne M, Goya RG. Physiology and therapeutic potential of the thymic peptide thymulin. Curr Pharm Des. 2014;20(29):4690-6. ↗
- Novoselova EG, Khrenov MO, Glushkova OV, Lunin SM, Parfenyuk SB, Novoselova TV, Fesenko EE. Anti-inflammatory effects of IKK inhibitor XII, thymulin, and fat-soluble antioxidants in LPS-treated mice. Mediators Inflamm. 2014;2014:724838. ↗
- da Silva AL, de Oliveira GP, Kim N, Cruz FF, Kitoko JZ, Blanco NG, Martini SV, Hanes J, Rocco PRM, Suk JS, Morales MM. Nanoparticle-based thymulin gene therapy therapeutically reverses key pathology of experimental allergic asthma. Sci Adv. 2020;6(24):eaay7973. ↗
- Parent G, Chevalier P, Zalles L, Sevilla R, Bustos M, Dhenin JM, Jambon B. In vitro lymphocyte-differentiating effects of thymulin (Zn-FTS) on lymphocyte subpopulations of severely malnourished children. Am J Clin Nutr. 1994;60(2):274-8. ↗
- Faure GC, Bène MC, Thomas P, Tamisier JN. An open trial of thymulin (FTS-Zn) in rheumatoid arthritis patients: sequential clinical and immunological follow-up. Clin Exp Rheumatol. 1987;5(3):291-3. ↗
- Khavinson VKh, Morozov VG. Peptides of pineal gland and thymus prolong human life. Neuro Endocrinol Lett. 2003;24(3-4):233-40. [Thymalin, a bovine thymic complex distinct from thymulin; cited only to mark the distinction.] ↗
- Consolini R, Legitimo A, Calleri A, Milani M. Distribution of age-related thymulin titres in normal subjects through the course of life. Clin Exp Immunol. 2000;121(3):444-7. ↗
- Faure G, Bène MC, Tamisier JN, Gaucher A, Duheille J. Thymulin (FTS-Zn) induced in vitro modulation of T cell subsets markers on lymphocytes from rheumatoid arthritis and systemic lupus erythematosus patients. Int J Immunopharmacol. 1984;6(4):381-8. ↗
- Saitoh N, Awaya A, Sakudo A, SungWook S, Saeki K, Matsumoto Y, Onodera T. Serum thymic factor prevents LPS-induced pancreatic cell damage in mice via up-regulation of Bcl-2 expression in pancreas. Microbiol Immunol. 2004;48(9):629-38. ↗
- Mizutani M, El-Fotoh M, Mori M, Ono K, Doi K, Awaya A, Matsumoto Y, Matsumoto Y. In vivo administration of serum thymic factor (FTS) prevents EMC-D virus-induced diabetes and myocarditis in BALB/cAJcl mice. Arch Virol. 1996;141(1):73-83. ↗
- Oliver MA, Marsh JA. In vivo thymulin treatments enhance avian lung natural killer cell cytotoxicity in response to infectious bronchitis virus. Int Immunopharmacol. 2003;3(1):107-13. ↗